Head coach Kyle Shanahan provided updates on QB Brock Purdy and other key injuries and reflected on the resilience and leadership shaping the 49ers 4-1 start.

San Francisco 49ers quarterback Brock Purdy missed another game on Sunday and hasn't practiced this week, but head coach Kyle Shanahan has no plans to place him on injured reserve.

SANTA CLARA, Calif. — San Francisco 49ers quarterback Brock Purdy was unable to practice Wednesday as he his still hampered by a toe injury that has sidelined him for three games already this season.

San Francisco 49ers quarterback Brock Purdy is still sidelined by a toe injury and missed practice on Wednesday.

There are several Buccaneers-49ers matchups to watch this weekend. Here is the Buccaneers biggest matchup advantage to focus on.

The Jacksonville Jaguars are placing tight end Brenton Strange on injured reserve, meaning he will be out for at least the next four weeks. Strange exited "Monday Night Football" in the second quarter ...

The San Francisco 49ers could have to make do without three of their top playmakers against the Tampa Bay Buccaneers.

The Brock Purdy vs Mac Jones problem seems real. The San Francisco 49ers regular starter, Purdy, did not practice on Wednesday and is unlikely to play the Week 6 matchup against the Tampa Bay ...

Brock Purdy aggravated his toe injury in the Week 4 loss to the Jaguars. Mac Jones is 3-0 in relief as a starter.

The San Francisco 49ers have dropped their first injury report of the week and it revealed bad news for Brock Purdy, Ricky Pearsall and Jauan Jennings.

While fans and media can't resist talk of a quarterback controversy, the San Francisco 49ers' quarterback situation is simple.

San Francisco 49ers quarterback Mac Jones has made the most of his opportunity while filling in for injured starter Brock Purdy. His strong play has sparked chatter about a possible quarterback ...