Isiah Pacheco — the Chiefs' lead back — has managed just 163 yards in five games, failing to reach the end zone. He is yet to tally 50 rushing yards in any one individual game this season.

Leading by a touchdown in the third quarter and knocking on the door of another score, Mahomes threw a 99-yard interception return to Jaguars linebacker Devin Lloyd. That was a backbreaking play for Kansas City and pushed momentum to Jacksonville's side.

Clemson head coach showed his support for Jacksonville Jaguars quarterback Trevor Lawrence after a big win against the Kansas City Chiefs.

Chiefs defensive back Chamarri Conner described his viewpoint of a late defensive pass-interference call, one of 13 K.C. penalties.

Wide receiver Odell Beckham Jr. is facing a six-game suspension and was a non-factor for the Miami Dolphins last season, but he is still holding out hope he will play for a contender at some point during the 2025 campaign.

The Kansas City Chiefs have struggled with penalties and close games this season. They lost to the Jacksonville Jaguars on Monday night, marking their third consecutive one-score loss.

The 49ers (4-1) travel across the country to face the Bucs (4-1), and both teams are coming off entertaining 3-point wins on the road. The 49ers — despite being riddled with injuries on offense — won Thursday night over the Rams as huge underdogs. Mac Jones filled in again for quarterback Brock Purdy and the 49ers offense looked good.

Jones deactivated his social media accounts Tuesday after drawing criticism for "standing and watching" on the game-deciding play.