Background: Diabetic nephropathy (DN) is a severe complication of diabetes, which has been increasingly associated with gut microbiota dysbiosis and inflammatory dysregulation. Objective: This study ...

Introduction: Following spinal cord injury (SCI), blood-borne monocytes infiltrate the spinal cord, differentiate into macrophages, and dominate the lesion site. Inflammatory responses mediated by ...

Abstract: Sperm DNA fragmentation is a critical factor in male infertility assessment, often evaluated using tests such as the Sperm Chromatin Structure Assay (SCSA) and the TUNEL assay. Despite their ...

Not developing potency assays and gaining knowledge about MOAs early in the drug development process not only can break ATMP success but can cause costs and delays that lead to company closures.

In a recent study published in the journal Cell Reports Medicine, researchers created small, laboratory-grown intestines, called organoids, from tissue samples of patients with Crohn's Disease (CD) to ...