Background: Interleukin-6 (IL-6) is a key proinflammatory cytokine regulating the humoral immune response by inducing B lymphocyte differentiation into plasma cells and stimulating antibody production ...

One of the main factors behind their incredible record has been the form of central-defender Maxime Esteve, who has been instrumental to the Clarets' run. However, with great performances comes ...

(Football Insider, external) Everton will make a move for Burnley's 22-year-old French centre-back Maxime Esteve if England international Jarrad Branthwaite, 22, leaves this summer. (Sun ...

The role of myeloid cells (granulocytes and monocytes) in neurodegeneration and neurodegenerative disorders (NDD) is indisputable. Here we discuss the roles of myeloid cells in neurodegenerative ...

Direct reprogramming of fibroblasts to neurons induces widespread cellular and transcriptional reconfiguration. Here, we characterized global epigenomic changes during the direct reprogramming of ...

S-Palmitoylation is the only reversible post-translational lipid modification. Knowledge about the DHHC palmitoyltransferase family is still limited. Here we show that human ZDHHC6, which modifies key ...

Post-translational modifications of DNA and histones are epigenetic mechanisms, which affect the chromatin structure, ultimately leading to gene expression changes. A number of different epigenetic ...