For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these ...

If most of our DNA is junk, could we cut those useless chains and still have a functional cell? This question was originally answered on Quora by Adriana Heguy.

Scientists at St. Jude Children's Research Hospital have reconciled two closely related but contentious mechanisms underlying ...

The figure analyzes the frequency at which mutation was induced in 40 bases of the target DNA sequence. In the nuclease model (left), mainly insertion and deletion are induced.

You also get to train on the genome itself: the genes as they are, next to each other on the genome. When you train a protein language model, you basically take a whole genome and cut out all the ...

Earlier this year, another group used genome editing to cut out the DNA sequence of a particular human protein the HIV virus latches onto. The latest study, ...

After a number of tweaks, Brec1 would cut only that sequence of DNA, patching up the cell’s genetic code once the HIV sequence was cleaved out. After 21 weeks, the cells treated with Brec1 ...