RNA polymerase II (Pol II) pause release and transcriptional elongation involve phosphorylation of TRIM28 by the DNA damage response (DDR) kinases. Here, Bunch et al. show that DDR signalling is ...

During elongation, the new RNA strand becomes longer and longer as the DNA template is transcribed. In this view, the 5' end of the RNA strand is in the foreground. Note the inclusion of uracil ...

Although the roles of the mammalian elongation factors G1 and G2 have not been studied, elongation factor G in prokaryotes hydrolyzes GTP 21 and, in so doing, catalyzes the translocation of ...

Mitochondrial deoxyribonucleic acid (mtDNA) is essential for cellular energy production and overall cell function.

By measuring ligand-induced DNA elongation at different ligand concentrations, they determined the binding constant and site size as a function of force.

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription and translation processes.

Pol I begins the process of DNA elongation at a point called the “origin of replication” and about 400 base pairs downstream of this point, Pol III takes over replication, which it performs at ...

Pyrophosphate-based sequencing is based on DNA elongation (sequencing-by-synthesis), and principally opposite to Sanger termination reaction.

“We found that the elongation factors Spt4/5 and Elf1 bind to functionally important parts of polymerase II,” says Sekine, adding that they act like subunits of the polymerase. Sekine likens the ...

Enzymatic methods for nucleic acid labeling DNA polymerase is an enzyme used to create DNA polymers by DNA elongation or primer extension processes.

“We found that the elongation factors Spt4/5 and Elf1 bind to functionally important parts of polymerase II,” says Sekine, adding that they act like subunits of the polymerase. Sekine likens the ...