Cucumbers, a summer staple of salads and sandwiches, are a valuable commercial crop. They also have a less well-known role as ...

A new analysis of the ancient DNA of 42 people from Papua New Guinea reveals that some cultures were remarkably isolated for centuries.

Mitochondrial deoxyribonucleic acid (mtDNA) is essential for cellular energy production and overall cell function.

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription and translation processes.

Unlike prokaryotic RNA polymerases that transcribe simple DNA templates, eukaryotic RNA polymerases transcribe DNA wrapped with nucleosomes. In yeast cells, the RNA polymerase II (Pol II) elongation ...

An old drug gets a new look: DNA damaging agent aclarubicin found to disrupt chromatin and stimulate RNA Pol II elongation ...

The State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China Transcription elongation is a fundamental molecular process which ...

We explored the regulatory mechanism of DNA methylation in response to salt and alkaline stress during cotton hypocotyl elongation. Our data shed light into the relationship of methylation regulation ...

Since DNA damage signaling is known to affect the fitness of HSCs, the data argue that caPOT1 mutations do not cause significant telomere damage. Furthermore, hESC lines with caPOT1 mutations showed ...

DNA–phenanthriplatin association consisted of fast and reversible DNA lengthening with time constant τ ≈ 10 s, followed by slow and irreversible DNA elongation that reached equilibrium in ∼30 min.

RNA polymerase II (Pol II) pause release and transcriptional elongation involve phosphorylation of TRIM28 by the DNA damage response (DDR) kinases. Here, Bunch et al. show that DDR signalling is ...