During elongation, the new RNA strand becomes longer and longer as the DNA template is transcribed. In this view, the 5' end of the RNA strand is in the foreground. Note the inclusion of uracil (yello ...
DNA intercalators are widely used as fluorescent probes to visualize DNA and DNA transactions in vivo and in vitro. It is well known that they perturb DNA structure and stability, which can in turn ...
The extent of heat-induced inhibition of DNA replication in HeLa cells was assayed at temperatures between 43 and 48°C. During hyperthermic exposure replicon initiation, as well as elongation of ...
The Cockayne syndrome B (CSB) protein is essential for transcription-coupled DNA repair (TCR), which is dependent on RNA polymerase II elongation. TCR is required to quickly remove the cytotoxic ...
Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...
Dr. Graham Erwin, assistant professor of molecular and human genetics at Baylor College of Medicine, has been awarded the National Institutes of ...
A plethora of chemical or enzymatic methods are available to generate nucleic acids such as those labeled with fluorophores, enzymes and radioactive phosphates, or nucleotides modified with ...
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