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As azide compounds play a central role in the synthesis of 1,2,3-triazoles in click chemistry, this method is expected to contribute to the efficient development of pharmaceuticals and other ...
Although these "trivalent" platforms enable the efficient synthesis of complex compounds, the selective formation of triazoles using platforms with azide and alkyne moieties remains an unsolved ...
Click chemistry has become an essential tool in applied chemistry due to its simplicity, efficiency, and versatility. This approach to chemical synthesis allows for quick and reliable joining of ...
Chemists need to be able to install the azide onto the aromatic ring, and the transformation doesn’t work with every azide because of competing reactions. He sees this version as a first ...
They made the compounds by reacting sodium azide with pyridines bearing two halogen atoms. This produced nine different fluoro-, chloro-, and bromo-azidopyridines in yields of 24–82%.
Click chemistry has become an essential tool in applied chemistry due to its simplicity, efficiency, and versatility. This approach to chemical synthesis allows for quick and reliable joining of ...
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