Template-assisted synthesis dramatically improves the yield of functionalized oligophenylene cages, report researchers from Japan.

The valine ester-molecule "looks" enough like the amino acid valine to be taken up by amino acid transporters and "carried" into cells. A few things worth noting. Unlike NHC and tenofovir, acyclovir ...

Review Article Published: 18 September 2008 Target profiling of small molecules by chemical proteomics Uwe Rix & Giulio Superti-Furga Nature Chemical Biology 5, 616–624 (2009) Cite this article ...

The NTHU team in Taiwan recently developed a novel strategy of directly introducing both trifluoromethyl and hydroxyl/amino hydroxyl synthon groups across alkenes with high enantioselectivities by ...

Dopa is a modified amino acid with one more hydroxyl group attached to tyrosine, and research on underwater adhesion started with the fact that Dopa makes up a large component of the adhesive protein.

By acetylating the amino groups or phosphorylating the hydroxyl groups, the AMEs change the polarity of the aminoglycosides which reduces their cellular permeability.