Chris Butler studied medicine at Gonville and Caius College, Cambridge (1991–1994) and then at the University of Edinburgh (1994–1997). He conducted his PhD on the syndrome of transient epileptic ...

Adult-onset leukodystrophies and genetic leukoencephalopathies comprise a diverse group of neurodegenerative disorders of white matter with a wide age of onset and phenotypic spectrum. Patients with ...

Introduction Huntington's Disease (HD) is an autosomal dominant neurodegenerative disease caused by polyglutamine repeat expansion in the Huntington ‘htt’ gene. HD is characterised by motor and ...

OBJECTIVES Deep brain stimulation of the basal ganglia has become a promising treatment option for patients with Parkinson's disease who have side effects from drugs. Which is the best target—globus ...

Mutations in the dysferlin gene lead to limb girdle muscular dystrophy 2B, Miyoshi myopathy and distal anterior compartment myopathy. A cohort of 36 patients affected by dysferlinopathy is described, ...

1 Department of Neurology, University of Virginia School of Medicine, Charlottesville, USA 2 Department of Health Evaluation Sciences, University of Virginia School of Medicine Correspondence to: Dr G ...

a Department of Clinical Psychology, St John’s Hospital, Howden Road West, Livingston, West Lothian EH54 6PP, Scotland, UK, b Department of Psychology, Stirling University, Stirling, Scotland, UK Dr ...

Objective To report the diagnostic utility of the Six-Item Cognitive Impairment Test (6CIT), a brief (2–3 minute) cognitive screening instrument, for the detection of dementia and mild cognitive ...

Background: Classification of traumatic brain injury (TBI) severity guides management and contributes to determination of prognosis. Common indicators of TBI severity include Glasgow Coma Scale (GCS) ...

Correspondence to Georgios Koutsis, Neurogenetics Unit, 1st Department of Neurology, School of Medicine, Eginition Hospital, National and Kapodistrian University of Athens, Athens 11528, Greece; ...

Background To compare the effectiveness and treatment persistence of ocrelizumab, cladribine and natalizumab in patients with relapsing–remitting multiple sclerosis switching from fingolimod. Methods ...

Aim We instinctively look towards faces expressing strong emotions such as fear. This survival-critical response – potentially alerting us to danger – requires rapid detection (sensory) and ...