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Researchers used a unique base-editing strategy to engineer chimeric-antigen receptor (CAR) T cells that engraft in the host and remain invisible to remaining antibody drugs. Of the 11 patients with T ...
1Division of Surgical Oncology, Dewitt Daughtry Department of Surgery, University of Miami, Miami, Florida. 2Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami ...
Abstract. Chimeric antigen receptor (CAR)-T cell therapy enables potent, antigen-specific immune responses and has demonstrated success in treating hematologic malignancies. However, conventional ex ...
2Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Illinois. 3Robert H. Lurie Comprehensive Cancer Center ...