A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.

Ultraviolet (UV) radiation is known to cause DNA damage, and while that damage may accumulate and eventually lead to diseases ...

For the first time, scientists have identified promising drug candidates that bind irreversibly with a notoriously ...

Researchers from Northwestern University have stumbled upon a previously unobserved function of a protein found in the cell ...

Sunburns and aging skin are obvious effects of exposure to harmful UV rays, tobacco smoke and other carcinogens. But the effects aren't just skin deep. Inside the body, DNA is literally being torn ...

Scientists have identified promising drug candidates that bind irreversibly with a notoriously “undruggable” cancer protein ...

As XPC steps back, the protein complex called transcription factor IIH, or TFIIH (pronounced T-F-2-H), moves into position.

For the first time scientists have identified promising drug candidates that bind irreversibly with a notoriously "undruggable" cancer protein target, permanently blocking it.