Cucumbers, a summer staple of salads and sandwiches, are a valuable commercial crop. They also have a less well-known role as ...

Cucumbers, a summer staple of salads and sandwiches, are a valuable commercial crop. They also have a less well-known role as ...

I was immediately and deeply interested in this problem because it inherently relied on the physicochemical properties of packed beds (specifically, the average shear rate generated by the mobile ...

Unlike prokaryotic RNA polymerases that transcribe simple DNA templates, eukaryotic RNA polymerases transcribe DNA wrapped with nucleosomes. In yeast cells, the RNA polymerase II (Pol II) elongation ...

In 2022, we reported the DNA sequences of 33 medieval people buried in a Jewish cemetery in Germany. Not long after we made the data publicly available, people started comparing their own DNA with ...

This work was supported by the Howard Hughes Medical Institute and the University of Washington Genome Training Grant. UW/Fred Hutch/Seattle Children’s Cancer Consortium member Steven Henikoff ...

The State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, China Transcription elongation is a fundamental molecular process which ...

Keywords: Gossypium barbadense, cell elongation, DNA methylation, high pH alkaline, responding Citation: Rui C, Zhang Y, Fan Y, Han M, Dai M, Wang Q, Chen X, Lu X, Wang D, Wang S, Gao W, Yu JZ and Ye ...

Since DNA damage signaling is known to affect the fitness of HSCs, the data argue that caPOT1 mutations do not cause significant telomere damage. Furthermore, hESC lines with caPOT1 mutations showed ...

Phenanthriplatin, a monofunctional anticancer agent derived from cisplatin, shows significantly more rapid DNA covalent-binding activity compared to its parent complex. To understand the underlying ...

“We found that the elongation factors Spt4/5 and Elf1 bind to functionally important parts of polymerase II,” says Sekine, adding that they act like subunits of the polymerase. Sekine likens the ...

RNA polymerase II (Pol II) pause release and transcriptional elongation involve phosphorylation of TRIM28 by the DNA damage response (DDR) kinases. Here, Bunch et al. show that DDR signalling is ...