August 24, 2010 — A novel sporadic prion protein disease, variably protease-sensitive prionopathy (VPSPr), with distinct features has been described as the first new prion disease since sporadic ...

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP. How these aggregates form ...

Kuru A virtually extinct form of human prion disease of the Fore linguistic group of Papua New Guinea transmitted via ritualistic endocannibalism. Mainly affected women and young children. Some ...

...this study describes a distinct ... phenotype with a non-CNS presentation... Human prion diseases are caused by propagation of abnormal prion protein, and are usually characterized by rapid ...

Prion diseases are rare and occur due to proteins in the brain that “misfold.” Another name for prion disease is transmissible spongiform encephalopathies (TSEs). There are many types of prion ...

New research from Japan suggests that a rare brain-destroying disease caused by rogue prion proteins may be becoming more common—likely due to an aging population. The study, published last month in ...

Prion diseases are rare, fatal neurodegenerative disorders caused by misfolded prion proteins (PrP) in the brain. This can lead to memory loss, behavior changes, and movement problems. Prion diseases ...

Close-up on three ropes and marine knots isolated on white background. Each is photographed separately. Prion diseases are rare but deadly neurodegenerative brain diseases that result from misfolding ...

The misfolded proteins responsible for a fatal neurological illness in deer have a twist. The first detailed structure of an infectious prion that causes chronic wasting disease, or CWD, reveals ...

The brain MRI is important for the diagnosis of prion disease for ruling out other possible etiologies, but it can also show features suggestive of prion disease. Brain MRI findings are found in most ...