Day 2 of the MLB draft involved rounds four through 20. Pitcher Riley Kelly from Tustin High and UC Irvine went to the Rockies with the 107th overall pick.

CHICAGO –– The White Sox continued a similar trend with their fourth-round pick in the 2025 MLB Draft. By selecting Landon Hodge 106th overall, the White Sox added their third high school hitter in their first four picks. The outlier is Kyle Lodise, a shortstop from Georgia Tech, the team's lone pick from the collegiate ranks at this point.