Two years after this, Sakaguchi was able to link these discoveries. He proved that the Foxp3 gene governs the development of ...

The Nobel Prize in Medicine was awarded on Monday to three scientists for discovering how a particular kind of cell can stop the body's immune system from attacking itself. The discovery of these ...

Dietary restriction reshapes CD8+ T cell metabolism by increasing ketone body–driven acetyl-CoA production, preventing ...

Cancer immunotherapy has transformed cancer treatment, yet many patients experience limited or short-lived responses due to ...

It develops from the abnormal multiplication of T cells, or T-lymphocytes, a type of white blood cell essential for immune system function. The specific treatment course and prognosis for T-cell ...

In 2006 immunologist Shimon Sakaguchi co-wrote an article in Scientific American that now feels prophetic. In the article, entitled “Peacekeepers of the Immune System,” Sakaguchi and his co-author, ...

A laboratory study out of Roswell Park Comprehensive Cancer Center outlines a new way to boost the effectiveness of chimeric ...