A ribosome is composed of two subunits: large and small. During translation, ribosomal subunits assemble together like a sandwich on the strand of mRNA, where they proceed to attract tRNA molecules ...

These spots are socRNAs being translated by ribosomes in a cell. They get brighter over time, showing active translation. The complex, which includes the socRNA and ribosome, is attached to the plasma ...

During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, these molecular decoders pause on the mRNA, either ...

Christine Dunham is a leading expert on the ribosome—an elaborate macro-molecular machine that operates like a factory within ...

Slower ribosomes stall during translation and collide with faster ones, triggering selective degradation of their small subunits. This “ribosome competition” mechanism ensures that only efficient ...

Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists ...

ReAberrant translation initiation at non-AUG start codons is associated with cancer and neurodegenerative diseases. Therefore, identifying how non-AUG translation is regulated differently from ...

Ribosomes can function with iron or manganese ions in place of magnesium, recent results show, providing an insight into the evolutionary history of protein transcription. A recent study that set out ...

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The ...