Figure 1: High-score SR protein motifs in exon 7 of SMN1 and SMN2. Figure 3: Exon 7–skipping correlates with disruption of the proximal SF2/ASF heptamer motif. Figure 4: The SMN1 SF2/ASF heptamer ...
For about three-quarters of human genes, individual or partial exons can be included in or excluded from different versions of the mature messenger RNA by alternative splicing 1. Many alternative ...
T cells from patients with systemic lupus erythematosus (SLE) produce insufficient amounts of the vital cytokine IL-2. We previously showed that SLE T cells express decreased levels of the T-cell ...
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