Cancers are populations of cells that are heterogeneous across space and through time. This diversity is currently a major clinical issue, limiting the efficiency of most cancer treatments as there is ...

For a long time, evolutionary biologists have thought that the genetic mutations that drive the evolution of genes and proteins are largely neutral: they're neither good nor bad, but just ordinary ...

A recent review by Carlo Maley, a researcher at Arizona State University, and Lucie Laplane from the University of Paris Pantheon-Sorbonne critiques the dominant theory of cancer evolution. The ...

In the 1960s, Kimura’s neutral theory revolutionized molecular biology by arguing most DNA changes are random, not adaptive. A new study finds beneficial mutations are far more common than Kimura’s ...

The idea that modern humans inherited DNA from Neanderthal ancestors is one of the 21st century’s most celebrated discoveries in evolution. It may not be that ...

A review examines the prevailing theory of cancer evolution. The authors highlight both practical and theoretical limitations of the clonal model of cancer evolution and propose areas for improving ...