Opioids are remarkably effective painkillers, but their effects in the brain can also cause euphoria, addiction, and fatal ...

Researchers found that Mindfulness-Oriented Recovery Enhancement (MORE) can help rewire the brain's response to natural healthy pleasure, leading to reduced opioid cravings. The findings suggest that ...

New research by Steven Laviolette's research team at Western University is contributing to a better understanding of the ways opiate-class drugs modify brain circuits to drive the addiction cycle.

Major scientific discoveries can arise from simple decisions: say, by simply looking where virtually no one else has. Such was the case for Ines Ibañez-Tallon, a research associate professor in the ...

More good news in the battle against opioid addiction. Scientists have reopened research into a class of opioids that were once shelved from study — and have discovered a variant that’s a powerful ...

Scientists have developed a new gene therapy that quiets pain at its source in the brain—without the addictive risks of opioids. Using AI to map how pain is processed, they created a targeted “off ...

Opioid use disorder is a devastating health crisis facing our communities. And for those seeking recovery, the medical ...

Rodrigo España, PhD, an assistant professor in the College of Medicine, was quoted in a June 27 Science News story about how hypocretin, a brain chemical that regulates wakefulness and arousal, may ...

Many of the drugs used in operating rooms are the same or close pharmacologic relatives to drugs involved in overdose deaths. Fentanyl changed the opioid epidemic, making opioid, cocaine, and other ...

Activation of the body’s opioid system may be required for ketamine’s antidepressant effects, new research hinted. In a small study of adults with major depressive disorder, taking the opioid blocker ...

Addiction decreases the brain’s ability to experience natural, healthy pleasure, driving increased cravings and compulsive substance use. But can this brain deficit be healed? New research from my lab ...

(The Hill) — Multiple states have raised the alarm in the past month about cychlorphine, a synthetic opioid tied to several dozen recent overdoses that is far stronger than fentanyl. Cychlorphine is ...