No. 15-ranked Texas Tech rolled past OSU 42-0 on Saturday at Jones AT&T Stadium, sending Oklahoma State to a seventh straight loss.

The Cowboys were riding high in the 2010s. OSU was the Big 12's second-best program behind OU. Texas Tech was the second-worst, ahead of only Kansas.

There's still a lot of football to be played, in other words. Week 12 gives us a couple of games pitting new guard versus old guard in SEC country, plus high-leverage contests in Pittsburgh, New Orleans and Harrisonburg, Virginia. Here's everything you need to follow on a big-as-ever mid-November Saturday.

No. 15 Texas Tech rolled to a 42-0 win over Oklahoma State on Saturday at Jones AT&T Stadium — a game that was exactly as lopsided as the score suggests.

Texas Tech’s football game against BYU is the biggest event in Lubbock since 2008. It has taken that long for the Red Raiders to get back. | Opinion

Texas Tech enters Saturday as 23.5-point favorites, according to ESPN Bet on Thursday, and the number is justifiable. All nine of the Red Raiders’ wins have been by 22 points or more this season, which is the first time a Big 12 school has accomplished that feat since 2009.

Oklahoma State and Texas Tech were scheduled to kick off at 3 p.m., but a weather delay will likely push back the Big 12 football game.

Each of the five players listed as out on the initial Big 12 Conference-mandated availability report, released Wednesday night, were also out for the Red Raiders' win over BYU last week. This list includes defensive lineman Skyler Gill-Howard; receivers T.J. West, Leyton Stone and Roy Alexander; and offensive lineman Hunter Zambrano.

The Red Raiders bounced back from their first loss to trounce the struggling Cowboys. Here are the highlights.

The biggest games of Week 12 in college football feature a pair of SEC games that will have significant playoff impact.