Cancers are associated with extensive reorganisation of epigenetic patterns, making identification of DNA methylation changes responsible for driving cancer development challenging. Here, we present a ...

Mechanisms by which prior tuberculosis (TB) increases long-term risk for cancer, cardiovascular, and neurological disorders remain unclear, particularly in people with HIV (PWH). This study ...

Different neuropsychiatric and neurodevelopmental conditions, such as schizophrenia, bipolar disorder, ...

Scientists found that some inherited traits can bypass the traditional rules of genetics, revealing a surprising new layer of ...

The role of innate immune system in modulating CHK1 inhibitor (CHK1i) response in BRCA wild-type (BRCAwt), platinum-resistant high-grade serous ovarian cancer (PR-HGSOC): Exploratory analysis from a ...

An AI model has been trained to recognize DNA methylation signatures of 13 different types of cancer. Researchers at the University of Cambridge and Imperial College London (both UK) present an AI ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in ...

CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA. DNA methylation is a process in which a methyl group is ...

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and is a major way that DNA is epigenetically marked. Epigenetic modifications can act as ...