The endonuclease activity of MLH1-MLH3 (MutLγ) is stimulated by MSH4-MSH5 (MutSγ), EXO1, and RFC-PCNA to resolve meiotic recombination intermediates such as double Holliday junctions (HJs) into ...
Homologous recombination is central to the repair of DNA double-strand breaks and the rescue of stalled replication forks. A pivotal intermediate in this process is the Holliday junction, a four-armed ...
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