Retrons adapted from E. coli enable genome editing in 15 diverse bacterial species, expanding recombineering tools across major microbial phyla.

Recent scientific advances have made genome editing technologies—a suite of biological tools for making precise additions, deletions, and alterations to the DNA and RNA of living cells– more rapid, ...

The ability to precisely edit the genomes of bacteria has long been a goal of microbiologists. Such technology would enable ...

Existing gene-editing technologies have led to significant advances in both medicine and food production. However, momentum appears to be slowing, particularly in health applications, as early hype is ...

A major collaboration involving nine labs, led by scientists at Gladstone Institutes, has transferred a particularly useful DNA editing system from E. coli into 14 new species of bacteria, spanning ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

Discover how prime editing is redefining the future of medicine by offering highly precise, safe, and versatile DNA corrections, bringing hope for more effective treatments for genetic diseases while ...

Like base editing, prime editing offers a safer way to genome editing by relying on a nickase enzyme that “nicks” one DNA strand at a time, rather than cutting both simultaneously. Then, with the ...

When a chef develops a new recipe, they methodically add and remove individual ingredients to see how each of them alters the final dish. When scientists try to understand the role of genes in the ...