Laboratory of Signalling and Cardiovascular Pathophysiology has the following research output in the current window (1 January 2025 - 31 December 2025) of the Nature Index. Click on Count to view a ...

Leukotrienes are bioactive lipid mediators derived from arachidonic acid through the concerted action of 5-lipoxygenase (5-LO) and its activating protein (FLAP). Two main classes exist: leukotriene B₄ ...

People with chronic kidney disease (CKD) are more likely to get heart disease. Using proteomics, the analysis of proteins, researchers developed a model to predict cardiovascular disease in CKD ...

A team of researchers from Ohio University's Heritage College of Osteopathic Medicine recently discovered a novel role of human-CIDEC gene in improving metabolic dysfunction and cardiovascular health.

Of the estimated five million patients in the U.S. diagnosed with heart failure annually, nearly half will have heart failure with preserved ejection fraction (HFpEF). Also known as diastolic heart ...

Drosophila -- known as fruit flies -- are a valuable model for human heart pathophysiology, including cardiac aging and cardiomyopathy. However, a choke point in evaluating fruit fly hearts is the ...

A diagonal ear lobe crease (DELC), or Frank’s sign, is a deep crease or wrinkle extending to the earlobe. Some studies suggest this indicates a greater risk for coronary artery disease, which can ...

Cardiovascular research is one of the key areas of interest of the Department of Molecular Physiology and Biophysics. Research by our faculty members focuses on a variety of subjects including ...

Researchers from Imperial College London's Department of Bioengineering and Faculty of Medicine worked alongside academics from UCL to produce sub-millimeter resolution images of cardiac micro-vessels ...

Sleep breathing disorders (SBDs)—including obstructive sleep apnoea, central sleep apnoea and sleep-related hypoventilation syndromes—represent a major yet under-recognised contributor to global ...