Human brain organoids are remarkable platforms for modeling features of human brain development and diseases. Building on methods to generate organoids to model different brain regions such as the ...

The prevalence of obesity is steadily rising and has huge health and financial implications for society. Weight gain is due to an imbalance between dietary intake and energy expenditure and research ...

To address this gap, Professor Wu Qingfeng's team focused on the arcuate nucleus (ARC) of the hypothalamus, a central hub for metabolic regulation. Within the ARC, two well-characterized neuronal ...

The influence of hormones on the development of brain circuits has long been recognized. A recent study shows that leptin has a similar effect on the emergence of feeding pathways. There might ...

Once it’s cleaved, the protein precursor pro-opiomelanocortin (POMC) gives rise to hormones involved in appetite, arousal, pleasure, and more. In this webinar, Stefan Radtke will discuss the ...

2DG-induced glucoprivation promotes high-carbohydrate diet (HCD) and high-fat diet (HFD) intakes in the paraventricular nucleus of the hypothalamus (PVH) by activating neuropeptide Y (NPY) neurons in ...

In a new discovery, researchers from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences have identified a previously underexplored population of hypothalamic ...